The fat molecule avocatin B, found in avocados, was shown to inhibit VLCAD, an enzyme vital for leukaemia cell metabolism.
Optical tweezers-coupled Raman spectroscopy has been used to reveal the structure of alpha-synuclein, an IDP linked to Parkinson's disease.
Researchers have shown that miR-29 can control brain maturation in mammals, presenting a target for autism, epilepsy and other conditions.
SARS-CoV-2 diverts building blocks from glucose production to the assembly of purine bases, researchers have found.
Researchers have developed a new tool that can add or remove sugar from proteins, which could be used to treat "undruggable" targets.
Researchers have shown that administering a UTI vaccine directly to the bladders of mice helped them to effectively fight bacteria.
A new compound can inhibit the build-up of plaque in arteries and prevent atherosclerosis, researchers have shown.
Studies in mice have shown that the drug ProAgio is effective at treating pancreatic cancer and triple-negative breast cancer.
A new therapeutic approach using the protein IL-21 could optimise the immune system, allowing it to combat HIV.
Researchers have developed a personalised medicine platform that they say could advance genomic medicine research for cancer.